O030 Reduction in fall risk markers following CPAP treatment of obstructive sleep apnoea in people over 65 years

Abstract Objectives Falls in older people can lead to serious injury and significant societal health financial burden. Obstructive sleep apnoea (OSA) is associated with impaired gait/balance may increase fall risk, yet few studies examined whether treating OSA reduces risk. This study the effect of continuous positive airway pressure (CPAP) on risk markers over 65yrs diagnosed OSA. Design Single arm intervention Setting University tertiary care CPAP clinic. Participants Individuals 65 years recommended CPAP. Intervention 3-6 months therapy Measurements All participants had a physiological profile assessment (PPA) at baseline following The PPA examines visual contrast sensitivity, lower limb proprioception, knee extension strength, reaction time postural sway generate score (FRS). t-tests were used determine difference between pre- post-treatment FRS. Regression was examine associations use daytime sleepiness Results significantly reduced FRS ([Mean±SD] 0.59±1.0 vs 0.04±1.1, p=0.016), sensitivity proprioception (P<005). Increased improvement unadjusted analysis (β=-0.213, 95%CI -0.371 -0.056, p=0.01). Reduction Epworth reduction (p=0.02) adjusted (p<0.03). Conclusions reduce 65yrs, possibly related better adherence sleepiness. Future controlled trials mechanistic are needed elucidate how